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subcutaneous nodules. Molecular mimicry between group A streptococci and heart tissue was first described by Kaplan in 1960 (41). In the early 1980s, the role of both humoral and cellular autoimmune responses was reported in several...

burdensome inflammatory skin disorders. AD is a chronic disease that is caused by a combination of genetic predisposition, skin-barrier disruption, immune factors, and environmental exposures. AD affects up to 15–20% of children and 1...

chronic, inflammatory disease of the joints. The joint swelling is accompanied by dry, red, and flaky skin. You could have relatively few skin lesions but many affected joints. Psoriatic arthritis often shows up from ages 30 to 50 years...

a chronic disease of the pilosebaceous unit that manifests clinically as non-inflammatory comedones or inflammatory papules, pustules, and nodules (Yentzer et al., 2010; Bhate and Williams, 2013). Three primary factors are implicated in...

Nodular Acne Accutane is indicated for the treatment of severe recalcitrant nodular acne. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. “Severe,” by definition...

the inflammatory reaction in each crystal deposition disorder varies and often is incompletely known. Monosodium Urate Crystal Deposition Disease (Gout) Gout is a systemic disease characterized by elevated serum uric acid levels to more...

an inflammatory response, leading to pulmonary edema and interstitial lung disease. Drug-induced systemic lupus erythematodes is an example of immune-mediated lung damage. Secondly, similar to other amphiphilic compounds, some drugs can...

the inflammatory response.26 One mode of action of aspirin is to intervene in this cascade at the level of cyclooxygenase activity by acetylation of a serine residue at the active site of the cyclooxygenases I and II, thereby...

The inflammatory response reached a plateau by six weeks. There were no remaining neutrophils; instead, giant cells, epithelioid cells, and fibroblasts constituted the major cell types present (Law, Parson, Silver, Et Weiss, 1989...