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of the T lymphocytes near the sinuses were abluminal (Fig. 1e). To confirm this finding, mice were injected intravenously (i.v.) with DyLight 488 lectin or fluorescent anti-CD45 antibody prior to sacrifice and the abluminal localization...

Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC). Early phase clinical trials have confirmed safety and indicated efficacy of...

high levels of miR-155, which represses PPAR-γ expression, thereby contributing to IR. Lean mice treated intravenously with these “obese” ATM exosomes develop glucose intolerance, hyperinsulinemia, and IR comparable with obese mice...

is a tightly controlled systemic inflammation model in which healthy volunteers are injected with bacterial LPS intravenously to elicit transient but profound acute hyperinflammation, followed by a late immunosuppressive phase14...