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세포 찌꺼기 청소 시스템.. autophagy ... 2021 nature review 2024.10.16해당카페글 미리보기
or Atg7 in Drosophila increase the levels of insoluble protein aggregates and reduce longevity30,71. Finally, knockout of Atg5 or Atg7 in mouse neurons leads to the appearance of cytoplasmic inclusion bodies in the brain and early-onset...
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만성염증 --＞ 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
to timing – that is, before, during, or after pre-antigen receptor signaling. Although no single NF-κB-subunit-knockout mouse has as severe a phenotype as NEMO knockouts with regard to the generation of mature lymphocytes, double...
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파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
in ARJP. Moreover, steady-state levels of the known parkin substrates were surprisingly unaltered in the parkin knockout mouse.7,8 Two-dimensional gel electrophoresis followed by mass spectrometry analysis revealed a decrease in the...
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Re: 산화질소, 황화수소 gaseous signaling 치료전략 2024.05.29해당카페글 미리보기
In this same study, myocardial oxidative stress and eNOS uncoupling were significantly increased in the CSE knockout mouse. The authors treated the CSE-deficient mice with H2S donor therapy for 7 days and reported significant increases...
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Re: Cathepsin B in programmed cell death machinery 2024.02.02해당카페글 미리보기
evidence of the pathophysiological roles and substrates of CatB has been reported following the establishment of CatB knockout mouse in 2000 [4]. CatB is synthesized as inactive pre-proenzymes and modified in their N‐glycosidically...
