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만성염증 --> 자가면역 염증으로 진행하는 과정의 중요 인자 NF-κB 탐구!! 2024.07.04해당카페글 미리보기
to timing – that is, before, during, or after pre-antigen receptor signaling. Although no single NF-κB-subunit-knockout mouse has as severe a phenotype as NEMO knockouts with regard to the generation of mature lymphocytes, double...
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파킨슨 병리 ... jama 논문.. 2024.07.10해당카페글 미리보기
in ARJP. Moreover, steady-state levels of the known parkin substrates were surprisingly unaltered in the parkin knockout mouse.7,8 Two-dimensional gel electrophoresis followed by mass spectrometry analysis revealed a decrease in the...
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Re: 산화질소, 황화수소 gaseous signaling 치료전략 2024.05.29해당카페글 미리보기
In this same study, myocardial oxidative stress and eNOS uncoupling were significantly increased in the CSE knockout mouse. The authors treated the CSE-deficient mice with H2S donor therapy for 7 days and reported significant increases...
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건선 .. 각질세포 과증식.. 자가면역... 2024.06.24해당카페글 미리보기
patients and IMQ-induced psoriasis mouse model. IL-17E injection caused psoriasis-like pathology in mouse skin, whereas global knockout of IL-17E ameliorated IMQ-induced psoriasis. Specially, IL-17E deficiency in keratinocytes could lead...
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Re: Cathepsin B in programmed cell death machinery 2024.02.02해당카페글 미리보기
evidence of the pathophysiological roles and substrates of CatB has been reported following the establishment of CatB knockout mouse in 2000 [4]. CatB is synthesized as inactive pre-proenzymes and modified in their N‐glycosidically...