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211). Cancer Chemotherapeutic resistance ▪ Chronic mtDNA stress causes upregulation of a specific subset of ISGs (IRDs) via the U-ISGF3 complex, promoting enhanced nuclear DNA repair. The chemotherapeutic drug doxorubicin causes mtDNA...

N-terminal kinases [JNKs] 및 p38)의 지속적인 활성화에 의존하는 것으로 밝혀졌습니다. 이와 유사하게, Yip 등은 디설피람-Cu2+ 복합체가 ROS 생성을 유도하고, 이로 인해 하류로 흐르는 세포사멸 관련 JNK 및 p38MAPK 경로를 활성화시켜 유방암 세포의...

Small Cell Lung Cancer)**과 **소세포폐암(SCLC, Small Cell Lung Cancer)**으로 나눌 수 있습니다. ​ (1) 비소세포폐암 (NSCLC...및 여성에서도 발생 가능 ​ 원위 세기관지(terminal bronchioles)에서 발생하여 종종 폐 주변부(peripheral lung)에 위치...

Airport Terminal 4. And one of the things he said, he said, in management, so many people come and complain about what you're doing. They say, you know, it's not good enough. You should make it more comfortable for everybody. And one of...

in lung cancer,18 Salmonella typhi in gallbladder cancer,19 Streptococcus bovis,20 Bacteroides fragilis21, and especially the periodontal pathogen Fusobacterium nucleatum in colon cancer.22 These studies have led to the possible role of...

had terminal cancer, based on weight loss and a palpable mass. He never had a formal tissue diagnosis, not unusual in the era prior to scans and needle biopsies, so the diagnosis was never confirmed. Kelley’s protocol included dietary...

in terminal human cancer. Proc Natl Acad Sci U S A. 1978;75:4538-4542. 18. Drisko JA, Chapman J, Hunter VJ. The use of antioxidants with first-line chemotherapy in two cases of ovarian cancer. J Am Coll Nutr. 2003;22:118-123. 19. Riordan...

N-terminal domain can oligomerize to form pores in the cell membrane, inducing cell membrane rupture (Fig. 3). Fig. 3: Schematic representation of CatB and its substrates in the core pyroptosis machinery. Activation of NLRP3 inflammasome...

carboxy terminal region with homology to R-SMADs and SMAD4 MH2 domains, antagonizes the activation of TGF-β receptor/SMAD signaling. SMAD7 achieves this via multiple mechanisms, including the recruitment of the E3 ubiquitin ligase SMURF...