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Re: 염증유발 과정에서 NF-κB signaling 탐구 .. 2024.07.04해당카페글 미리보기
as pore-forming toxins, viral RNAs, ATP and crystalline substances.60,64 These diverse stimuli are thought to activate NLRP3 via inducing different cellular events, including K+ efflux, Ca2+ signaling, mitochondrial and lysosomal damages...
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Cellular Senescence in Brain Aging 2022.10.07해당카페글 미리보기
gene expression profile of aged neurons and, eventually, to neuronal dysfunction. Moreover, impairment of nuclear pores (nuclear pore “leakiness”) contributes to age-related changes in the nucleus and cytoplasm configuration...
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성인의 심장이 재생되지 않는 이유를 설명합니다 2022.10.27해당카페글 미리보기
날짜: 2022년 10월 24일 원천: 피츠버그 대학교 요약: 새로운 연구에 따르면 쥐에서 심장 세포가 성숙함에 따라 핵공(nuclear pore)이라고 불리는 통신 경로의 수가 급격히 감소합니다. 이것은 손상 신호로부터 기관을 보호할 수 있지만 성인 심장 세포가...
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Re: Cathepsin B in programmed cell death machinery 2024.02.02해당카페글 미리보기
Bak pore formation, either by directly activating Bax/Bak or passively by sequestering the anti-apoptotic Bcl-2 proteins. Once active Bax/Bak have induced mitochondrial outer membrane permeabilization, pro-apoptotic factors such as...
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Mitochondrion 2023.08.19해당카페글 미리보기
the pore-forming voltage-dependent anion channel (VDAC). The VDAC is the primary transporter of nucleotides, ions and metabolites between the cytosol and the intermembrane space.[23][24] It is formed as a beta barrel that spans the outer...
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Re: ER stress - oxidative stress, inflammation의 이해 2023.08.24해당카페글 미리보기
conserved nuclear protein TDP43 encoded by the TARDBP gene also contributes significantly to the occurrence of ALS [3,45]. As a major hallmark of NDs, protein aggregation, and their accumulation in different parts of the central nervous...
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3/26: What is your stance on nuclear power? 2011.04.29해당카페글 미리보기
that nuclear energy will emit comparable quantities of CO2 from an equivalent combined cycle gas-fired plant. However, this is only the first industrial infrastructure involved in atomic electricity. After mining the uranium ore is...
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Trump's lawyer defends his comment that 'Kim begged on hands and knees’ to revive S'pore summit 2018.06.07해당카페글 미리보기
S'pore summit FILE PHOTO: Rudy Giuliani delivers remarks before Donald Trump rallies with supporters in Council Bluffs, Iowa, US, September 28, 2016. Reuters file photo Updated 07 June, 2018 WASHINGTON — United States President Donald...
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cell death를 일으키는 미토콘드리아 기능의 손상지점 - membrane permeablization 2023.07.12해당카페글 미리보기
trigger nuclear apoptosis (466, 742, 891). However, proteomic analysis of the supernatants of mitochondria with permeabilized OM revealed that Cyt c and AIF are released together with numerous other key proteins, including but not...
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Re: Regulation of Intestinal Barrier Function by Microbial Metabolites 2022.10.09해당카페글 미리보기
the pore pathway, the leak pathway allows macromolecule flux with an exclusion limit of ∼100 Å with lower conductance.51 The leak pathway is believed to be regulated by myosin light-chain kinase (MLCK), where constitutively active MLCK...