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Visceral pain is triggered by central targeted stimuli (neonatal stress and posttraumatic stress disorder) or peripherally targeted stimuli (infection and inflammation)17. In rodent models, neonatal maternal deprivation (NMD) and colonic...

at both 4 weeks (acute phase) and 16 weeks (chronic phase). Importantly, systemic administration of anakinra, a peripherally restricted IL-1 receptor antagonist, only inhibited nociceptive behaviors at 4 weeks but not 16 weeks, but...

as well as interacting with the inner cellular scaffolding proteins and the actin cytoskeleton [11]. ZOs are peripherally associated proteins that interact with claudins, occludins, and JAMs to anchor the membrane proteins, tethering...

what is the relevance of this discussion for the majority of the world's population?those who participate only peripherally in the global industrial system? One striking characteristic of underdevelopment is the relative absence of...