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under study (28). Mitochondria are considered as the redox-active compartment within the cell, accounting for nearly 90% of oxygen utilization (1). They serve as a significant contributor to ROS in the form of O2•-. Mitochondrial SOD...

recent study suggests that DET1 physically interacts with COP1. DET1 mediates the COP1-HY5 interaction and is necessary for the destabilization of COP1 in a light-independent manner. DET1-mediated COP1 destabilization is necessary for...

the pivotal role of GCIs in neuronal death [81, 147], and additionally, both lesions increase with disease duration [148-150]. In the SN, severe neuronal loss is accompanied by low GCI density, indicating that this and other areas...

a pivotal role in regulating neuronal energy metabolism, neurotransmission, cell repair, and maintenance in the brain, and therefore exerkines may act via impacting brain mitochondria to improve brain function and disease resistance...

under study, in particular PPARα/δ (i.e., possesses dual activity on both PPAR-αand PPAR-δ receptors) and PPARα/γ agonists. The PPARα component increases fatty acid oxidation, whereas the PPARδ component has anti-inflammatory...

a pivotal role in shouting the truth in this wrong society that kills everyone, and saving people. It has been more than 10 years since I have taken medicine or been to the hospital, and prepares to become a leader, and of course, my own...

effects among unexposed rats that were treated with DMSA, compared with unexposed, untreated rats. This pivotal animal study led to cancellation of a large, much-publicized trial in children. In assessing the relevance for the trial...

the Study of War and AEI's Critical Threats Project By Samuel Granados In just over a week, Syrian rebel forces seized much of Syria’s northwest. First, the rebels captured Syria’s largest city, Aleppo, then Hama and Homs. On Sunday...

recent study found that, over nine years (from 2009 to 2018), more than 550,000 individuals were afflicted by PNI in the United States. Moreover, the incidence rate has more than doubled throughout that period of time [3]. Such injuries...