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an active fibroblast illustrating differential receptor engagement by hyaluronan fragments. Long HMW-HA chains preferentially bind and cluster CD44 at the cell surface, promoting structural integrity and anti-inflammatory signaling...

L-lactate accumulates in several types of cancer as a result of the Warburg effect [4], where cancer cells preferentially reduce pyruvate to L-lactate (Fig. 1). While lactate production is typical under physiological conditions of...

56 CDK4 knockout embryos develop normally, suggesting that CDK4 is not essential for proper mouse development but preferentially affects overall postnatal growth.57 Indeed, they exhibit hypoplasia of various organs, decreased body weight...

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injected, CAG repeat-targeting siRNA containing acyclic serinol nucleic acids is widely distributed throughout the central nervous system and preferentially silences polyglutamine-expanded proteins, while preserving the levels www.cell.com

the head is erect, the utricle is oriented nearly perpendicular to the line of gravity, therefore the hair cells preferentially respond when the head is tilted with respect to gravity or during linear accelerations. In contrast, the...

and NADS11; however, these organs also utilize the machinery for salvage. Lung, WAT, testis, and skeletal muscle preferentially rely on salvage and have low expression of proteins involved in the Preiss–Handler pathway41, with the...

related neoplasm.48 Recommendation: In 2023, patients with ICUS/CHIP/CCUS should not be treated but followed preferentially in a dedicated “CHIP” clinic. Attention should be paid to the care of comorbidities. Clinical trials could be...

non-α-RGCs to a growth-competent state. By contrast, SOX11 expression kills α-RGCs, the cellular subtype that preferentially regenerates following treatments such as PTEN deletion143. SOX11 expression also promotes CST regeneration...