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Re: Pathophysiology of Pain and Mechanisms of Neuromodulation: A Narrative 2026.10.06해당카페글 미리보기
function within the central nervous system after the discovery that nociceptive peripheral nerve injuries could sensitize peripheral nociceptive terminals.39,40,64–66 Central sensitization is implicated in multiple rheumatologic and...
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Re: 미토콘드리아 기능부전이 어떻게 유전체 불안정성 --> 유전자 돌연변이 암을 일으키는가? 2024 네이처 2026.09.26해당카페글 미리보기
역할 대표 단백질 살리는 쪽 (anti-apoptotic) BCL-2, BCL-XL, MCL-1, BCL-w 죽이는 쪽 (pro-apoptotic effector) BAX, BAK sensitize 하는 쪽 (BH3-only) BIM, BID, BAD, NOXA, PUMA 암은 살리는 쪽을 올리고 죽이는 쪽을 막아 아폽토시스 문턱을...
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Re: minority MOMP --> 악성종양 암... 최신 논문 탐구!! 2026.08.26해당카페글 미리보기
to resist the chemotherapeutic agent 5-fluorouracil in colorectal cancer cells [85]. Alternatively, ATF4 may sensitize cancer to specific therapies, including BCL-2 inhibition in acute myeloid leukemia [86]. It was also shown that...
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삼차 신경통 원인, 예후, 만성통증 .. 문치연 치료법 최신 논문 탐구!! 2026.05.07해당카페글 미리보기
in the altered molecular environment, peripheral trigeminovascular neurons become sensitised, and in turn, sensitize second and third order trigeminovascular neurons in the spinal trigeminal nucleus and the thalamus.38,44 Intensification...
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Re: 근막이 통증의 주범, TrP 통증 최신 논문 이해!! 2026.09.08해당카페글 미리보기
thickening, and densification, reducing mobility and elasticity (42). These changes impair tissue mechanics and sensitize embedded nociceptors (43). Emerging mechanobiological data suggest that fascial fibrosis, adhesions and impaired...