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of systemic inflammation, such as high-sensitivity C-reactive protein (CRP), and acute-phase protein [91], serum amyloid A, cytokines such as IL-6, and adhesion molecules such as soluble intercellular adhesion molecule type 1 (ICAM-1...

the amyloid precursor protein by α-, β- and γ-secretases (2,3). Monomeric Aβ is prone to the change in its conformation to β-sheet-rich intermediate structures. The intermediates interact with each other to form multimeric...

and has a protective effect against chronic colitis [169]. Further studies found that SFB induced serum amyloid A (SAA) production in the terminal ileum and that SAA action on LP dendritic cells (DCs) promoted IL-22 secretion, increased...

as amyloid via paravenous drainage pathways (Iliff et al., 2012; Xie et al., 2013; Mestre et al., 2018) and has been visualized in human patients via magnetic resonance imaging (MRI; Meng et al., 2019; Fultz et al., 2019). Expression of...