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From here, the other cut end of the cable still on the seafloor can be hoisted aboard, and the two sides can be spliced together. All of this typically takes days. To ensure that the newly lengthened cable doesn’t stray from its...

into a single sequence) and the proline-glutamate-valine-lysine (PEVK) element located between the differentially spliced and distal Ig domains (39). The PEVK element and the Ig domains collectively represent the most critical elastic...

Middle: protein domains expressed in the N2A isoform of skeletal muscle titin (consensus sequence). Differentially spliced titin segments are indicated. FnIII, fibronectin type-III-like; Ig, immunoglobulin-like; PEVK, protein domain rich...

G-proteins. For example, the mGluR1 and mGluR5 subunit subtypes, which exist in a number of alternatively spliced forms, are coupled to the inositol trisphosphate (IP3)/Ca2+ signal transduction pathway and can thus affect protein kinase...