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as an inhibitor of apoptosis; Intracellularly, can function as a promoter of apoptosis [127] P53 Cytosol Tumor suppressor, transcription factor [48] Lon Protease Mitochondrial matrix Inhibits apoptosis by stabilizing mtHsp60, stabilizes...

Keilholz U: Natural T cell immunity against cancer.Clin Cancer Res, 9, 4296‐4303, 2003 19)Shevach EM: CD4＋CD25＋suppressor T cells: More questions than answers. Nat Rev Immunol, 2, 389‐400, 2002 20)Armitage JO: Emerging applications...

나타난다. 1. 유발 인자(Inducer Factor) : 유발 인자/조력인 자의 기능 즉 면역을 유발하는 기능을 한다. 2. 억제인자(Suppressor Factor) : 억제하는 기능을 가진다. 유발 인자는 전이인자(Transfer Factor)의 구성요소로서 기증과의 확실하게 성숙된...

by Wu et al. In MPP+-treated astrocytes and MPTP-injected mice, the authors have identified miR-543–3p as a suppressor of GLT-1 protein and mRNA expression, and hence of its transport activity.46 Furthermore, miR-543–3p inhibition was...

2004, the FDA has approved three other epigenetic drugs that are thought to work at least in part by stimulating tumor-suppressor genes that disease has silenced. The great hope for ongoing epigenetic research is that with the flick of a...

Alterations in Neoplastic Cells PDAC is caused, at least in part, by somatic mutations in oncogenes and tumor suppressor genes (Figure 2). The most commonly mutated genes in PDAC, the oncogene KRAS and the tumor suppressor genes CDKN2...

전기, 전자, 통신기기를 서지 전압으로부터 안전하게 보호하기 위해서는 서지프로택터(서지보호기 Surge Protector or Suppressor)의 설치가 필요하다 beachcomber noun [ C ] a person who walks along beaches looking for objects of value or interest...

the expression level of miRNA-203, inhibiting the negative regulatory molecule-cytokine signal transfer to suppressor of cytokine signaling-3 (SOCS3) function, thereby inhibiting cell apoptosis.96 P. gingivalis invades into the cell and...

of murine macrophages with the TLR7 agonist, gardiquimod, and the TLR9 agonist, CpG DNA, resulted in a suppressor of cytokine signaling-1-mediated reduction of TNF-α and IL-6 (129). These studies demonstrate multiple mechanisms that...