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labelled enteric neurons many days after the application of tracers to autonomic ganglia46. It is also unclear how synaptic connections between neurons and neurotransmission can persist if nerve cell bodies are turning over so rapidly47...

뇌 발달 과정에서 나타나는 현저성 네트워크의 변화는 특히 중요한 의미를 가질 수 있는데, 이 시기는 뇌의 ‘가지치기(synaptic pruning)’ 과정이 활발히 일어나는 때로, 불필요한 신경 연결은 제거되고 중요한 연결은 강화되는 시기이다. 따라서 신경...

consequences since only the maturing neurons carry unique features by displaying higher excitability and stronger synaptic plasticity [15]. In other words, because the temporal window, in which new neurons are particularly functional, is...

and Pietropaolo, 2011). GAD65 is a super autoantigen with high level of presence in the brain (Nataf, 2017). GAD65 is a synaptic enzyme that catalyzes y-aminobutyric acid (GABA) from glutamate. Its expression in inhibitory terminals is...

to become effective. A silent synapse cannot generate an action potential in the postsynaptic neuron; at most, synaptic activity in it leads to only a small excitatory post-synaptic potential. One of the mechanisms by which silent...

the aggregation of β-amyloid, the most component of senile plaques in AD. Taurine was also capable of inducing the synaptic potentiation and late phase long-term potentiation, which was accompanied with improved cognitive performance in...

brain barrier) increases short-term memory in rats (maze test) APAMIN: blocks Ca2+ dependent K + channels enhances long-term synaptic transmission shortens duration of a nerve's action potential HYALURONIDASE:DOPAMINE (neurotransmitter...

cognitive impairments and reduction of multiple AD-linked pathological characteristics such as inflammatory responses, synaptic loss, amyloid plaque burden and β-amyloid production by inhibition of JNK activation in mice after...

70세 이후에 발현이 감소합니다. [14] 이 세트에는 학습과 기억, 소포 수송 및 미토콘드리아 기능에 중요한 시냅스 가소성(synaptic plasticity)에 중요한 기능을 하는 유전자가 포함되어 있습니다. 노화가 진행되는 동안, 전두엽 피질(frontal cortex)의...