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conduction block으로 감각 신호 전달 차단. Small fiber vs Large fiber: 전통적으로 large myelinated fiber(진동·위치감각)가 취약하다고 했으나, 최신 증거에서는 small fiber(무수초 C-fiber, Aδ-fiber)가 초기에 먼저 손상되거나 기능 이상을 보임...

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and block IgE-FcϵRI binding faster, indicating that it is more efficient than omalizumab, causing the dissociation of preformed ligand-receptor complexes (85). 3.2. Interfering intracellular signalling pathways MC activation is...

cells block the cell cycle in G2 and do not initiate mitosis thanks to the activation of the G2/M checkpoint, linking DNA damage response to cell cycle progression.42,43 To ensure that cell cycle progress and arrest as necessary, cell...