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with CVD, as well as with frailty, disability, and mortality in older individuals, and the mechanisms that underlie these associations have only just begun to be elucidated. Controversy exists on whether high levels of pro-inflammatory...

evidence continues to suggest that nutrient excess elicits a chronic low-grade inflammatory response that may underlie cardiometabolic complications, which has expanded into the study of “metaflammation” (4). Here, we present an...

or injection-based interventions (67). These findings suggest that fascial change, not just muscle treatment, may underlie clinical benefit. Ultrasound (including shear-wave elastography) increasingly documents fascial thickening and...

circuitries. For instance, fatty acid binding protein 4 (FABP4) expression in ovarian cancer cells appears to underlie a mechanism that promote lipolysis in cancer-associated adipocytes. This results in the secretion of fatty acids that...