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in itself, it has temporality. It shows that it is fulfilled with time. It is not conditional in the world but unfolded with time. It is seen not in accordance with condition but in accordance with time. 언약의 삶은 이루어지는 시간, 혹은...

matrix (TID-1S), cytosol (TID-1L) Co-chaperone, stimulates Hsp70 ATPase activity [120] PERK / IRE1/ ATF6 ER lumen Unfolded protein response [121] Lon protease Mitochondrial matrix Inhibits apoptosis by stabilizing mtHsp60, stabilizes Hsp...

with the stretch force and becomes physiologically significant at forces of ≥4 pN/titin. Upon release, the unfolded Ig domains perform a folding contraction under force, which generates work during the transition to a molten globule...

ER dysfunction. To restore ER function and the balance between protein degradation and protein biosynthesis/folding, unfolded or misfolded proteins activate three stress sensors (PERK, ATF6 and IRE1) that initiate distinct pathways known...